Facilities

The Salomon Laboratory combines dedicated wet-lab space with immediate access to the Brown Proteomics Core Facility, creating an integrated environment for high-sensitivity, reproducible studies of T cell and CAR T cell signaling.

Integrated laboratory

Our 1,000-square-foot laboratory is on the fourth floor of 70 Ship Street in Providence’s Jewelry District, immediately adjacent to the Brown Proteomics Core Facility.

Advanced equipment

  • Orbitrap Ascend Tribrid Mass Spectrometer with FAIMS
  • Vanquish Neo UHPLC with EasySpray and NanoFlex sources
  • TECAN A200 automated sample preparation
  • Q Exactive Orbitrap with UltiMate3000 nanoRSLC for pilot studies

Mechanistic research

Our research program combines biochemistry, cell biology, quantitative phosphoproteomics, and computational analysis to uncover mechanisms of signaling and disease. Collaboration with the Brown Proteomics Core expands our technical capabilities.

Advanced Capabilities for Mechanistic Signaling Research

Advanced mass spectrometry at Brown. Dr. Nicholas DaSilva with the Thermo Scientific Orbitrap Ascend Tribrid Mass Spectrometer. The instrument is located in the shared instrument room immediately adjacent to the Salomon Laboratory, giving Salomon Lab trainees and personnel direct, 24/7 walk-up access. The Orbitrap Ascend was acquired with NIH support (1S10OD036295-01; PI: A. Salomon).